MYTH PERCEPTION THREE
(Ref.
Book – Excerpts from Spontaneous Evolution, Authors: Bruce H.
Lipton and Steve Bhaerman)
As repeatedly propagated by Swami
Vijnananand, we have been mentioning in these blogs the role of mind,
the importance and inevitability of mind's role for inclusion in the
scope of science. Such opinions are echoed by a few scientists and
thinkers in the 21st century. Next blog to follow aso
cover this topics.
When
Darwin put forth his heredity-based theory of evolution, the premise
that traits were passed from parent to child made perfect practical
sense to anyone who bred animals, like beget like.
Because
the Newton view at the time emphasized the primacy of matter, it was
seemingly assured that the secret of life would be encoded within the
body’s own molecule.
Shortly
after the turn of 19th century, American geneticist and
embryologist Thomas Hunt Morgan deduced that genetic factor that
control heredity traits are arranged along the chromosome in a
precise linear order. Further chemical analysis revealed that
chromosomes are compresses of proteins and Deoxyribo Nucleic Acid
(DNA). However the question as to whether the genetic key was the
protein or the DNA remained until 1944 when Oswald Avery, Colin Mac
Leod, and Maclyn McCarty (researchers from Rockefeller) determined
empirically that DNA was the molecule that determined heredity
traits. While this study was the first to distinguish DNA as the
heredity-controlling molecule, it did not offer any insight into
how DNA accomplished this feat.
In
1953, Watson and Crick changed the course of human history when their
article was published in the British scientific journal ‘Nature’.
Based on the nature of DNA coding mechanism, they posited
(postulated) the concept known as ‘central dogma of molecular
biology’. This is also referred to as ‘the primacy of DNA’.
Central dogma mapped the flow of information in most biological
systems being one directional: from DNA to RNA to protein.
Even
before Watson and Crick were born, science had concluded that an
assembly of physical molecules controls life. The only unanswered
question was: “which molecule would it be”? When Watson and Crick
reported their DNA results, the decision was a slam dunk (a task in
which the success is deemed a certainty): DNA molecules control life.
Amazingly,
biologists immediately adopted this central dogma hypothesis even
though its validity was never assessed. But was this DNA primacy
really true?
The
key implication in this is: heredity information only flows in one
direction, from DNA to RNA to Protein and never goes to the opposite
direction. Which means protein cannot influence the structure and
activity of the DNA code.
Here
is the problem: the body that experiences life is made out of
protein; because proteins cannot send information of life’s
experience back to DNA, then environmental information cannot change
genetic destiny. This means that genetic information is disconnected
from the environment.
Genetic
determination is the belief that genes control all of our
traits-physical, behavioral, and emotional. Simply it is the belief
that our fates are locked in our genes and because we cannot change
our genes, we are truly, so they say, victims of our heredity.
However
as the time went on, new discoveries undermined the surety of that
belief. In the late 1960s, University of Wisconsin geneticist Howard
Temin put forward his research publication which suggested that RNA
information could flow backward and alter the host cell’s DNA code.
Though Temin findings were not accepted initially, he ultimately
shared the Nobel Prize in Physiology. Temin’s work broke the
backbone of Crick’s central dogma by proving that hereditary
information flows in both directions. The hereditary changes can
be made by design or environmental influence and not only by
accidental mutation as had been presumed.
By
1990, as reported by Duke University biologist H. Frederik Nijhout,
genes are not ‘self-emergent’ and cannot ‘turn themselves on
and off’. Genes are just like books. They don’t read themselves.
Then who is responsible for reading genes? In Nijhout’s words:
“When a gene product is needed a signal from its environment
activates the expression of that gene”. Simply put ‘environmental
signal controls gene activity’.
Epigenetics:
Biomedical
sciences are being philosophically transformed by the new science of
Epigenetic control. It describes how gene activity and cellular
expressions are ultimately regulated by information from the external
field or influence rather than by the internal matter of DNA.
Though
this truth that genes do not control their own activity, was
established more than 20 years back, basic science books, media, and
especially the pharmaceutical industry continue to resist the
movement away from the central dogma. They, thus perpetuate the
layperson’s view that genes control their lives.
Mainstream
media continues to focus on the concept that genes are controlling
our lives. Every day new articles claim that gene has been found to
control this trait or that trait. The concept of genetic determinism
is so (deep and full of resonance) with the prevailing basal
paradigm (basic pattern) that even irrefutable scientific proof
cannot dislodge it.
Mind and Epigenetics:
The
science of epigenetics recognizes that the environment, not the DNA
in nucleus, determines the action of the cell. Information from the
environment is translated into biological responses via the action of
cell membrane, which acts as the cell’s skin as well as its brain.
The description of the cell membrane is same as computer chip. The
cell as well as the computer; both are programmable. And the
programmer is always outside the mechanism. Who can be the biological
programmer? Who or what is the genius behind the genes? The genius
behind the genes is none other than our own minds, our own thoughts
and beliefs.
The
process of Nature and Nurture is what shapes human mind through
thoughts and beliefs. The role of the mind assumes
significant importance not only in personal health but more important
holistic health. To make this role of mind more suitable, the
scientific study of the mind and proper training to the mind should
be the priority.
Here
again we see that the new research in the initial years of the 21st
century support the views Swami Vijnananand mentioned while he wrote
about the evolution and the role of mind in his books published in
1960s.
Vijay
R. Joshi.